The University of the Philippines Open University (UPOU) presents “Quality Initiatives in an Open and Distance e-Learning Institution: Towards Excellence and Equity”. The book outlines the evolution of the concept of quality in higher education and how it has been applied in Open and Distance Learning (ODL) and identifies relevant issues in a technology-enhanced education system. It also compiles the thoughts, practices, and initiatives of the University of the Philippines Open University, as an Open and Distance e-Learning (ODeL) institution, in achieving quality education under an open education philosophy which promotes inclusivity through universal accessibility, equity, and openness.